All six passengers presumed dead after plane went missing off US coast

Six people aboard a medical transport aircraft that went missing on Saturday while it was travelling from Bermuda to Boston are presumed dead, according to a statement from the flight's operator.

On Sunday evening, the United States Coast Guard said it was ending its search for survivors off the coast of Nantucket, a Massachusetts island.

"We must now face the heartbreaking reality that the four members of our Latitude team, our patient and the patient's family escort, who were aboard Heartbeat 104, are presumed to have died," Latitude Air Ambulance said in a statement shortly thereafter.