Opioid Overdose Deaths: National Trends and Variation by Demographics and States

Since the opioid epidemic was declared a public health emergency in 2017, it has claimed more than half a million lives. While the epidemic was initially driven by prescription opioids and heroin, it has evolved in recent years, to be dominated by illicit synthetic fentanyl—a substance significantly more potent than morphine. By 2023, most counterfeit opioid pills contained a deadly dose. As of 2022, nearly 1 in 3 adults reported in a KFF survey that they or a family member have been addicted to opioids (29%).