US surgeons perform first pig-to-human kidney transplant

A 62-year-man with end-stage renal disease has become the first human to receive a new kidney from a genetically modified pig, doctors from Massachusetts General Hospital in Boston announced on Thursday.

The four-hour surgery, performed on March 16, “marks a major milestone in the quest to provide more readily available organs to patients,” the hospital said in a statement.

The patient, Richard Slayman of Weymouth, Massachusetts, is recovering well and expected to be discharged soon, the hospital said.

Slayman had received a transplant of a human kidney at the same hospital in 2018 after seven years on dialysis, but the organ failed after five years and he had resumed dialysis treatments.

The kidney was provided by eGenesis of Cambridge, Massachusetts, from a pig that had been genetically edited to remove genes that could be harmful to a human recipient and add certain human genes to improve compatibility. The company also inactivated certain viruses inherent to pigs that have the potential to infect humans.