New technology puts a spatial lens on CRISPR screening

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility: Recently, scientists have been able to explore gene circuitry in individual cells using methods that suppress particular genes and measure the impact on the expression of other genes. These methods, however, fail to capture spatial information such as the effects from, or on, neighboring cells, which can provide important clues to a cell or gene's role in health and disease. Now, a technology developed in...