AstraZeneca COVID-19 vaccine 100% effective at preventing hospitalizations, company says

New data from AstraZeneca’s coronavirus vaccine trial, which has yet to receive emergency authorization in the United States, is showing positive results.

The latest data from the company published on Monday showed that the vaccine has an efficacy of 79% at preventing symptomatic cases of the coronavirus while being 100% effective at stopping severe disease and hospitalization. The trial included 32,449 participants, and a fifth of them, approximately 8,000 people, were 65 years old or older. 60% of study participants have comorbidities that make them more at risk for a more severe bout with the virus.

“These findings reconfirm previous results observed in AZD1222 trials across all adult populations, but it’s exciting to see similar efficacy results in people over 65 for the first time,” Ann Falsey, professor of medicine, co-lead principal investigator for the trial, said. “This analysis validates the AstraZeneca COVID-19 vaccine as a much-needed additional vaccination option, offering confidence that adults of all ages can benefit from protection against the virus.”

The findings will be submitted to the Food and Drug Administration for emergency use authorization in the “coming weeks,” and the company will be submitting their findings to a peer-reviewed journal as well.

Of the participants, less than half of 1%, 0.43% or 141 people, experienced a symptomatic case of the coronavirus.

Unlike other COVID-19 vaccines that have been approved already, the two doses of the AstraZeneca vaccine were administered four weeks apart, and “previous trials have shown that an extended interval of up to 12 weeks demonstrated greater efficacy, which was also supported by immunogenicity data.”

The Data Safety Monitoring Board found no safety concerns for “thrombotic events.”