The Supreme Court seems poised to seriously curtail abortion rights nationwide after arguments Wednesday in a Mississippi case.

The case, Dobbs v. Jackson Women's Health Organization, tests whether laws that ban pre-viability abortions are constitutional.

All of the court's past abortion decisions have upheld Roe's central framework: That pregnant people have a constitutional right to an abortion in the first two trimesters of pregnancy when a fetus is unable to survive outside the womb — roughly the first 24 weeks, reports NPR's Nina Totenberg.

In this case, Mississippi is asking the court to reverse its prior decisions guaranteeing abortion rights and throw the question back to individual states.

Unlike the last major case concerning Roe v. Wade, today's supermajority of six conservative justices all have a history of opposing abortion rights. Those justices' questions suggested they were open to siding with Mississippi and significantly rolling back Roe v. Wade.